Mewtwo

Mewtwo, The Genetic Pokémon. It was created in a lab by a scientist after years of gene splicing and DNA engineering. It's DNA is very close to Mew's. However it's size and stature is different.. Because it's Battling Abilities are at the Ultimate Level...it only thinks about defeating it's foes. It tends to remain motionless to conserve energy so it can unleash it's full power in battle. It's said to rest quietly in an undiscovered cave, it was created solely for battles. Although the Scientists managed to create Mewtwo, they couldn't give it a compassionate heart. It was turned vicious due to the experiments and gene splicing it was subjected to.

Battle Moveset

A Good Moveset for Mewtwo would have to be this:

Attacks:

Calm Mind
Recover
Psychic
Hidden Power Dark

Items Attached:

Salac Berry

Preferred Nature:

Modest

Strategy Using Mewtwo

Mewtwo is quite simply, one of the strongest legendaries and 00ber Pokemon available in the game. Its stats are all average or above, Special attack and Speed being its greatest stats.
It also has decent HP, which will allow for Recover to be used effectively. Calm mind will boost this Pokemon's sweeping abilities with the increase in special attack and special defense.
The other two moves are there to sweep your opponent, although HP Dark can be replaced with a variety of different special type moves (look in the Pokedex for possible replacements).
Psychic is obviously useful because of the strength it gains from STAB and can be quite powerful after Mewtwo has done a few calm minds.
Mewtwo can also be used as an all out sweeper, without the use of Calm mind, like this: Psychic, Ice beam, Thunderbolt, Flamethrower. Or why not make it a sunny beamer: Sunny day, Solarbeam, Flamethrower, Psychic.
There is plenty of choices to use for Mewtwo, just play around with what it can learn and it adjust it to your team needs. Otherwise, its still an 00ber legendary, so I wouldn't use it.

EV Corner:

Max out the EVs in Special Attack & Speed for Mewtwo with any remaining in Special Defense

Strategy Against Mewtwo

Mewtwo' Defenses are equal and a fair bit above Average so a Dark or Bug-type volley should make short work of this Genetic Abomination.

Contest Moveset

A good Contest Moveset for Mewtwo would have to be this for the Beauty Contest best with Modest, Mild, Rash or Quiet Nature:

Attacks:

Hail
Ice Beam
Rain Dance
Water Pulse

Items Attached:

Blue Scarf

Strategy Using Mewtwo

If you do the attacks in this following order you should have very few problems; 1st - Hail, 2nd - Ice beam, 3rd - Rain dance, 4th - Water pulse, 5th - Hail

Locations in Games

Ruby/Sapphire

Trade from FR/LG

Colosseum

Trade from FR/LG

Fire Red/Leaf Green

Cerulean Cave (Only One)

Animé Appearences

Mewtwo has had a few Animé Appearence. In it, it was created using Mew's DNA and enhanced by order of Giovanni to create the Ultimate Pokémon. After it destroyed the lab, it joined Giovanni. It sooned learnt it was nothing more than a slave and broke free. It decided to remove the world of humans and their Pokémon Slaves leaving the world open for itself and it's clone Pokémon. However it was stopped by Mew & Ash. After that it was in Johto in Paradise with it's clones when Giovanni managed to track it down and tried to get it back under his control.

Episode 063: Battle For The Badge!
Episode 064: It's Mr. Mime Time!
Origin Of Mewtwo!
Movie 1: Mewtwo Strikes Back!
Special 2: Mewtwo Returns!

 
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